[Cardiotoxicity of tricyclic antidepressive agents. (Phenothiazines and imipramines)].
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منابع مشابه
Application of Capillary Electrophoresis to Analysis of Tricyclic Psychotropic Drugs
Two separation modes of capillary electrophoresis (CE): capillary zone electrophoresis (CZE) and micellar electrokinetic capillary chromatography (MECC) were used for toxicological analysis of blood samples and pharmaceutical preparations. These two techniques were tested on commonly used phenothiazines (PHE) and tricyclic antidepressants (TCA), which are drugs of forensic interest. The analyti...
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EMETIC AND ANTIEMETIC DRUGS 4.1. Neuroleptics 4.1.1. Phenothiazines 4.1.2. Butyrophenones and Related Compounds 4.1.3. Substituted Benzamides; Metoclopramide. Sulpiride and Others 4.2. Antihistamines 4.3. Miscellaneous Antiemetic Drugs 4.3.1. 4.3.2. 4.3.3. 4.3.4. 4.3.5. 4.3.6. 4.3.7. 4.3.8. 4.3.9. 4.3.10. Cannabinoids Steroids Domperidone Anxiolytics and Sedatives Analgesics Tricyclic Antidepre...
متن کاملBuflomedil is a potent interfering substance in immunoassays of tricyclic antidepressants.
A 16-year-old boy in a coma (Glasgow scale 3) with general seizures was admitted to the intensive care unit. No palpable pulse necessitated cardiac massage. A blood specimen submitted to this laboratory tested positive for tricyclic antidepressants (TCA) by EMIT (Behring, Cupertino, CA) and negative by FPIA (Abbott, Wiesbaden, Germany). A number of antidepressants were screened for in blood by ...
متن کاملCardiotoxicity of amitriptyline and doxepin.
The cardiotoxicity of the tricyclic antidepressants amitriptyline and doxepin were compared in an animal with acute overdose. The mean repetitive extrasystole threshold (RET) decreased 71.5% with amitriptyline and 27.5% with doxepin (mean blood levels 933 ng/ml and 1889 ng/ml). Physostigmine reversed these effects. Sodium bicarbonate had a variable effect on the lowered RET. The toxic arrhythmo...
متن کاملCardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report
Poisoning with tricyclic antidepressants is an important cause of drug-related self-poisoning in the developed world and a very common cause of poisoning and mortality in developing countries. Electrocardiographic manifestations of most tricyclic antidepressant-poisoned patients resolve by the administration of 1-2 mEq/kg of sodium bicarbonate. Some rare cases have been reported who have been r...
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عنوان ژورنال:
- Schweizerische medizinische Wochenschrift
دوره 101 1 شماره
صفحات -
تاریخ انتشار 1971